The Rosamund Stone Zander Translational Neuroscience Center strives to accelerate the development of therapeutic options for children with brain disorders by fostering timely and efficient translational research.
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Featured News & Events
September 3-4, 2025: Global Genes Rare Drug Development Symposium (RDDS) in Boston, MA
September 3-4, 2025 in Boston, MA, at the Joseph B. Martin Conference Center at Harvard Medical School. Connect with leading experts and drive meaningful change in rare disease research.
IDEFINE commits $300,000 to launch natural history study of Kleefstra Syndrome with Boston Children's Hospital
IDefine – The Kleefstra Syndrome Foundation today announced a $300,000 grant to help launch a groundbreaking natural history study at Boston Children’s Hospital’s Rosamund Stone Zander Translational Neuroscience Center (RSZ TNC). The three-year study will advance critical research and help prepare the Kleefstra syndrome (KS) community for future clinical trials.
Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders
In this review, RSZ TNC researchers compare two-dimensional and three-dimensional human-induced pluripotent stem cell (hiPSC) formats for disease modeling, discuss the applications of functional assays, and offer insights on incorporating machine learning into hiPSC-based neurodevelopmental disorder research and drug screening.